Sonja Prustomersky Selected Research

cafestol

1/2003	Coffee and its chemopreventive components Kahweol and Cafestol increase the activity of O6-methylguanine-DNA methyltransferase in rat liver--comparison with phase II xenobiotic metabolism.
1/2003	Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.
1/2002	The coffee components kahweol and cafestol induce gamma-glutamylcysteine synthetase, the rate limiting enzyme of chemoprotective glutathione synthesis, in several organs of the rat.

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Sonja Prustomersky Research Topics

Disease

4	Neoplasms (Cancer) 04/2008 - 01/2002
2	Colonic Neoplasms (Colon Cancer) 01/2003 - 05/2002
1	Staphylococcal Infections 03/2005
1	Hepatocellular Carcinoma (Hepatoma) 01/2003

Drug/Important Bio-Agent (IBA)

3	Coffee FDA Link 04/2008 - 01/2002
3	cafestolIBA 01/2003 - 01/2002
3	kahweolIBA 01/2003 - 01/2002
1	VaccinesIBA 03/2005
1	AntigensIBA 03/2005
1	DiterpenesIBA 01/2003
1	allyl sulfideIBA 01/2003
1	EnzymesIBA 01/2003
1	Glutamate-Cysteine LigaseIBA 01/2003
1	Glutathione (Reduced Glutathione)IBA 01/2003
1	QuercetinIBA 01/2003
1	benzyl isothiocyanateIBA 01/2003
1	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA 05/2002
1	MutagensIBA 05/2002
1	AminesIBA 01/2002
1	Aflatoxin B1 (Aflatoxin B)IBA 01/2002

Therapy/Procedure

1	Chemoprevention 01/2003